Anion binding by biotin[6]uril in water.

نویسندگان

  • Micke Lisbjerg
  • Bjarne E Nielsen
  • Birgitte O Milhøj
  • Stephan P A Sauer
  • Michael Pittelkow
چکیده

In this contribution we show that the newly discovered 6 + 6 biotin-formaldehyde macrocycle Biotin[6]uril binds a variety of anionic guest molecules in water. We discuss how and why the anions are bound based on data obtained using NMR spectroscopy, mass spectrometry, isothermal titration calorimetry (ITC), computational calculations and single crystal X-ray crystallography.

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عنوان ژورنال:
  • Organic & biomolecular chemistry

دوره 13 2  شماره 

صفحات  -

تاریخ انتشار 2015